NuMat Medtech arises in 2016 as a result of the merger between Sanifit Medtech and NuMat Biomedical. Sanifit Medtech was a spin-off of Laboratoris Sanifit, a leading biopharmaceutical company focused on treatments for progressive vascular calcification disorders. NuMat Biomedical was created by Marta Monjo, Ph.D. in Molecular Biology with 15+ years of experience in research in biomaterials.

In 2013, NuMat Biomedical and Sanifit Medtech initiated a collaborative Project (PHYTECH) aimed at designing and developing new materials for bone implants. This project was funded by INNPACTO Project from the Spanish Ministry of Science and Innovation and by a Eurostars Project.

After completion of the project, the two companies decided to join efforts to better take advantage of the synergies between them and created NuMat Medtech.